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Trials
Safety and Efficacy of OBX-115 in Advanced Solid Tumors

trialsTrialRecruiting

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

A phase 1/2 trial of OBX-115 in melanoma and non-small-cell lung cancer, run by Obsidian Therapeutics, Inc., now recruiting.

Also called: Agni-01

Overview Connected3

Overview

Safety and Efficacy of OBX-115 in Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06060613 by Obsidian Therapeutics, Inc., with 208 participants planned, started 2023-10-25 and due to reach its primary completion in 2029-06-30. Interventions recorded: OBX-115.

Setting

A Phase 1/2, Open-Label Study to Investigate the Safety and Efficacy of Membrane Bound IL15 Expressing Tumor-Infiltrating Lymphocytes (OBX-115) In Participants With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Obsidian Therapeutics, Inc.

Registry

Started

2023-10-25

Enrolled

208 enrolled

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cancers

Melanoma Non-small-cell lung cancer

companies

Obsidian Therapeutics

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
208 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT06060613

Data

JSON ·

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Cancers

Melanoma
Non-small-cell lung cancer

Companies

Obsidian Therapeutics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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