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CPTAC (Clinical Proteomic Tumor Analysis Consortium)
CPTAC measures the proteins, not just the genes, of thousands of tumours.
Also called: CPTAC pipelinesClinical Proteomic Tumor Analysis Consortium
Overview
CPTAC, the Clinical Proteomic Tumor Analysis Consortium, holds proteogenomic data, mass spectrometry proteomics and phosphoproteomics, on tumours linked to TCGA, measuring the proteins rather than just the genes of thousands of tumours. This reveals pathway activity and ADC target abundance that DNA and RNA profiling miss. The consortium is run by the NCI and the data are open. On OnCo it is tied to the technology Proteomics and phosphoproteomics, cited by the bottleneck Data silos and the idea Link single-cell and spatial tumour atlases to clinical outcomes, and referenced by the journal record Cancer Cell and the Drug discovery roadmap.
Holds
Proteogenomic data (mass spectrometry proteomics and phosphoproteomics) on TCGA-linked tumours.
Licence
Open
Maintainer
NCI
Dataset registry
Size: Proteogenomic profiles on more than 1,000 TCGA-linked tumours
Access: controlled
Consent and reuse: Open processed data; controlled raw data through dbGaP.
All datasets and the models trained on them →Similar pages
- TermReverse-phase protein array (RPPA)
Shares Deep mass-spectrometry proteome (CPTAC), Proteomics & phosphoproteomics, Cancer AI vocabulary (CanSim terms map).
- TermPathway activation state (phosphosignalling)
Shares Deep mass-spectrometry proteome (CPTAC), mRNA to protein concordance, Proteomics & phosphoproteomics, Cancer AI vocabulary (CanSim terms map).
- TermPost-transcriptional and post-translational regulation
Shares mRNA to protein concordance, Cancer AI vocabulary (CanSim terms map).
- TargetE2F7
Shares mRNA to protein concordance, Cancer AI vocabulary (CanSim terms map).
- TargetDCLK1
Shares mRNA to protein concordance, Cancer AI vocabulary (CanSim terms map).
- CollectionTCGA / NCI Genomic Data Commons
Shares Link single-cell and spatial tumour atlases to clinical outcomes, Drug discovery roadmap: screening in mice → maps of dependency → designing in silico, Data silos, Cancer AI vocabulary (CanSim terms map).
- TargetPHLPP2
Shares mRNA to protein concordance, Cancer AI vocabulary (CanSim terms map).
- TargetDNAJC12
Shares mRNA to protein concordance, Cancer AI vocabulary (CanSim terms map).
technologies
institutions
terms
roadmaps
ideas
bottlenecks
journals
Open-source projects
All open source in oncology →Open-source projects that are the code behind this collection or publish it, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
A Python package that streams CPTAC proteogenomic cancer datasets into pandas.