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Trials
A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

trialsTrialRecruiting

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

A phase 1/2 trial of Pembrolizumab in advanced solid tumours, run by Arvinas Inc., now recruiting.

Overview Connected4

Overview

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07749586 by Arvinas Inc., with 499 participants planned, started 2026-07-29 and due to reach its primary completion in 2031-03-31. Interventions recorded: ARV-6723, Pembrolizumab and SOC.

Setting

A Phase 1/2 Open-label Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of ARV-6723 Administered as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Arvinas Inc.

Registry

Started

2026-07-29

Enrolled

499 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Pembrolizumab · Keytruda / Keytruda Qlex (SC)

companies

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
499 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07749586

Data

JSON ·

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Cancers

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Immune checkpoint inhibitors

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Arvinas

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