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Trials
Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies

trialsTrialRecruiting

Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies

A phase 1/2 trial of Pembrolizumab in advanced solid tumours, run by PharmaMar, now recruiting.

Overview Connected4

Overview

Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies is a phase 1/2 interventional study registered as NCT07644039 by PharmaMar, with 119 participants planned, started 2026-05-21 and due to reach its primary completion in 2029-04-02. Interventions recorded: Pembrolizumab and PM54.

Setting

A Multicenter, Open-label, Phase 1/2 Safety Run-in and Expansion Study of PM54 in Combination With Immunotherapy Evaluating Safety and Efficacy in Adult Participants Who Were Previously Treated for Advanced Malignancies

Phase

Phase 1/2

Sponsor

PharmaMar

Registry

Started

2026-05-21

Enrolled

119 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Pembrolizumab · Keytruda / Keytruda Qlex (SC)

companies

Evidence strength23/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
119 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07644039

Data

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Immune checkpoint inhibitors

Products

Pembrolizumab

Companies

PharmaMar

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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