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Trials
INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

trialsTrialRecruiting

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

A phase 3 trial of Sapablursen in myeloproliferative neoplasms, run by Ono Pharmaceutical Co., Ltd., now recruiting.

Also called: INTREPID

Overview Connected3

Overview

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV) is a phase 3 interventional study registered as NCT07429266 by Ono Pharmaceutical Co., Ltd., with 250 participants planned, started 2026-05-25 and due to reach its primary completion in 2028-09. Interventions recorded: Sapablursen and Placebo.

Setting

A Phase 3 Randomized, Double-blind, Placebo-controlled Global Study of Sapablursen in Polycythemia Vera

Phase

Phase 3

Sponsor

Ono Pharmaceutical Co., Ltd.

Registry

Started

2026-05-25

Enrolled

250 enrolled

Connected

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cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)Polycythaemia vera (PV)

companies

Deciphera Pharmaceuticals (Ono)

Evidence strength42/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 3+30
250 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT07429266

Data

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Cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)
Polycythaemia vera (PV)

Companies

Deciphera Pharmaceuticals (Ono)

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