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Trials
A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

trialsTrialActive

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

A phase 2 trial of DISC-3405 in myeloproliferative neoplasms, run by Disc Medicine, Inc, active and no longer recruiting.

Overview Connected3

Overview

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) is a phase 2 interventional study registered as NCT06985147 by Disc Medicine, Inc, with 60 participants enrolled, started 2025-08-12 and due to reach its primary completion in 2027-02. Interventions recorded: DISC-3405.

Setting

A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DISC-3405 in Participants With Polycythemia Vera (PV)

Phase

Phase 2

Sponsor

Disc Medicine, Inc

Registry

Started

2025-08-12

Enrolled

60 enrolled

Connected

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cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)Polycythaemia vera (PV)

companies

Evidence strength24/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
60 enrolled+9
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT06985147

Data

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Cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)
Polycythaemia vera (PV)

Companies

Disc Medicine

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Machine-readable versions of A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

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