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Trials
A Study of RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

trialsTrialRecruiting

A Study of RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

A phase 1/2 trial of Docetaxel and Bevacizumab in advanced solid tumours, run by RemeGen Co., Ltd., now recruiting.

Overview Connected4

Overview

A Study of RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors is a phase 1/2 interventional study registered as NCT06016062 by RemeGen Co., Ltd., with 221 participants planned, started 2023-09-14 and due to reach its primary completion in 2025-12-31. Interventions recorded: RC148 Monotherapy, RC148+docetaxel Combination Therapy, RC148+RC48 Combination Therapy, RC148+RC88 Combination Therapy and RC148/Bevacizumab+RC88 Combination Therapy.

Setting

A Multi-center Phase I/II Trial to Evaluate the Efficacy and Safety of RC148 As a Single Agent and Combination Therapy in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Phase

Phase 1/2

Sponsor

RemeGen Co., Ltd.

Registry

Started

2023-09-14

Enrolled

221 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedMonoclonal antibody (anti-VEGF)

Bevacizumab · Avastin (and biosimilars)

ApprovedCytotoxic chemotherapy (taxane)

Docetaxel · Taxotere (generic)

companies

Evidence strength25/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
221 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06016062

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

Docetaxel
Bevacizumab

Companies

RemeGen

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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