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Trials
A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignant Tumors

trialsTrialRecruiting

A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignant Tumors

A phase 2 trial of Carboplatin and Bevacizumab in advanced solid tumours, run by Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., now recruiting.

Overview Connected4

Overview

A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignant Tumors is a phase 2 interventional study registered as NCT07448922 by Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., with 280 participants planned, started 2026-04-08 and due to reach its primary completion in 2027-12-31. Interventions recorded: SKB518 for injection, Carboplatin (AUC 5) and Bevacizumab.

Setting

An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignancies

Phase

Phase 2

Sponsor

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Registry

Started

2026-04-08

Enrolled

280 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedMonoclonal antibody (anti-VEGF)

Bevacizumab · Avastin (and biosimilars)

ApprovedCytotoxic chemotherapy (platinum)

companies

Sichuan Kelun-Biotech

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
280 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07448922

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

Carboplatin
Bevacizumab

Companies

Sichuan Kelun-Biotech

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