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Trials
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

trialsTrialActive

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

A phase 1/2 trial of FOLFOX, Gemcitabine in metastatic cancer, run by Transcenta Therapeutics (Hangzhou) Co., Ltd., active and no longer recruiting.

Overview Connected5

Overview

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT04396821 by Transcenta Therapeutics (Hangzhou) Co., Ltd., with 150 participants planned, started 2020-05-28 and due to reach its primary completion in 2026-05-30. Interventions recorded: TST001, Nivolumab Injection [Opdivo], mFOLFOX6, Gemcitabine, Albumin-Bound Paclitaxel. Conditions listed: Advanced Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, Pancreatic Cancer. No results are recorded here; the registry entry is the source.

Setting

A Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of TST001 Administered as Monotherapy or in Combination With Nivolumab or Standard of Care in Patients With Locally Advanced or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

Transcenta Therapeutics (Hangzhou) Co., Ltd.

Registry

Started

2020-05-28

Enrolled

150 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedCytotoxic regimen

FOLFOX (5-FU, leucovorin, oxaliplatin)

ApprovedNucleoside analogue (deoxycytidine)

Gemcitabine · Gemzar / Infugem

Phase 2Monoclonal antibody

companies

Evidence strength24/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
150 enrolled+11
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-17 · Jude Gomila · Reverse links for orphaned drugs and companies · diff · file

Sources & links

ClinicalTrials.gov NCT04396821

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

FOLFOX (5-FU, leucovorin, oxaliplatin)
Gemcitabine
TST001

Companies

Transcenta

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