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Trials
Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms

trialsTrialActive

Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms

A phase 2 trial of Givinostat in myeloproliferative neoplasms, run by Italfarmaco, active and no longer recruiting.

Overview Connected3

Overview

Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms is a phase 2 interventional study registered as NCT01761968 by Italfarmaco, with 90 participants enrolled, started 2013-03 and due to reach its primary completion in 2026-12. Interventions recorded: givinostat.

Setting

Long-term Study Evaluating the Effect of Givinostat in Patients With JAK2V617F Positive Chronic Myeloproliferative Neoplasms

Phase

Phase 2

Sponsor

Italfarmaco

Registry

Started

2013-03

Enrolled

90 enrolled

Connected

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cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)

drugs

Phase 3small molecule

companies

Evidence strength25/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
90 enrolled+10
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT01761968

Data

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Cancers

Myeloproliferative neoplasms (PV, ET, myelofibrosis)

Products

Givinostat

Companies

Italfarmaco

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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