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A complete response means every measurable trace of the cancer has disappeared on scans or in the marrow; a partial response means it has shrunk by at least 30% (RECIST) but is still there. Neither is the same as cure: microscopic disease can remain.
Solid tumour responses are defined by RECIST 1.1 (complete: all target lesions gone and nodes <10 mm; partial: ≥30% decrease in summed diameters; progressive: ≥20% increase or new lesions; stable: neither); lymphoma uses Lugano and PET; leukaemia uses marrow blast count and count recovery (CR, CRi for incomplete recovery); myeloma uses IMWG (stringent CR, VGPR, PR). Complete responses are the strongest single-arm signal and, when durable, drive accelerated approvals; the proportion of complete responders and the depth of response (MRD, ctDNA clearance) increasingly predict long-term outcome. In neoadjuvant settings pathological complete response is judged on the resected specimen, and clinical complete response guides organ preservation.
Shares Progressive disease and radiographic progression, RECIST, Objective response rate (ORR).
Shares RECIST, Objective response rate (ORR).
Shares Blasts (leukaemic blast cells), Undetectable MRD (uMRD / MRD-negative).
Shares RECIST, Objective response rate (ORR).
Shares Objective response rate (ORR), Pathologic complete response (pCR).
Shares RECIST, Objective response rate (ORR), Pathologic complete response (pCR).
Shares RECIST, Objective response rate (ORR).