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Coffee does not cause cancer: IARC downgraded it in 2016, and cohort studies link two to three cups a day with lower rates of liver and womb cancer. Drinks of any kind served above 65 C are classed as a probable cause of oesophageal cancer, so the temperature, not the coffee, is the risk.
IARC reclassified coffee in 2016 from 'possibly carcinogenic' (Group 2B, a 1991 verdict driven by confounding with smoking) to 'not classifiable' (Group 3), while classifying beverages drunk above 65 C as Group 2A for oesophageal squamous cell carcinoma. Umbrella reviews of prospective cohorts show coffee consumption associated with lower risk of hepatocellular carcinoma (about 30-40% lower per 2-3 cups/day, the most consistent finding, including in people with liver disease) and endometrial cancer, and with lower cancer mortality; associations with other sites are null. After diagnosis, coffee intake was associated with lower recurrence and death in the CALGB 89803 colon cancer cohort and in advanced colorectal cancer (CALGB 80405), findings that are hypothesis-generating and unconfirmed by trials. Green tea and its catechins have not delivered in randomised chemoprevention trials (prostate, breast). This is an example of an exposure that generates endless headlines but has a stable, modest evidence base: coffee is safe, probably good for the liver, and not a treatment.
Coffee polyphenols, diterpenes and caffeine improve insulin sensitivity, reduce hepatic fibrosis markers and induce hepatic detoxifying enzymes; the protective association is strongest where those mechanisms are most relevant (liver, endometrium).
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One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
Query for this technology: (TITLE:"Coffee and tea intake" OR ABSTRACT:"Coffee and tea intake") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Coffee and tea intake, not a curated reading list.
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Shares International Agency for Research on Cancer (IARC / WHO), Misinformation and unproven therapies, Oesophageal cancer, Hepatocellular carcinoma.
Shares International Agency for Research on Cancer (IARC / WHO), Misinformation and unproven therapies, Oesophageal cancer, Hepatocellular carcinoma.
Shares International Agency for Research on Cancer (IARC / WHO), Endometrial cancer, Oesophageal cancer, Hepatocellular carcinoma.
Shares International Agency for Research on Cancer (IARC / WHO), Misinformation and unproven therapies, Oesophageal cancer, Hepatocellular carcinoma.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies.
Shares Misinformation and unproven therapies, Oesophageal cancer, Hepatocellular carcinoma, Colorectal cancer.