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Led IMPORT LOW, which showed partial-breast radiotherapy is as effective as whole-breast treatment with fewer side effects.
Charlotte Coles was chief investigator of IMPORT LOW, the UK trial showing partial-breast radiotherapy after breast conservation matches whole-breast radiotherapy for local control with less breast hardening, and co-led IMPORT HIGH and the PRIMETIME study of radiotherapy omission. She chaired the Lancet Breast Cancer Commission and is a leader in ESTRO. Her work drives the shift to shorter, more targeted breast radiotherapy.
Shares IMRT / IGRT (modern external beam), HR-positive / HER2-negative breast cancer and the tags radiotherapy, breast.
Shares IMRT / IGRT (modern external beam), HR-positive / HER2-negative breast cancer and the tags radiotherapy, breast.
Shares Cancer Research UK Cambridge Centre / CRUK Cambridge Institute, HR-positive / HER2-negative breast cancer.
Shares IMRT / IGRT (modern external beam), HR-positive / HER2-negative breast cancer and the tags radiotherapy, breast.
Shares Cancer Research UK Cambridge Centre / CRUK Cambridge Institute and the tags breast, de-escalation.
Shares European Society for Radiotherapy and Oncology and the tag radiotherapy.
Shares European Society for Radiotherapy and Oncology and the tag radiotherapy.
Shares HR-positive / HER2-negative breast cancer and the tags breast, de-escalation.