Visual examination of the mouth by trained health workers reduced oral cancer deaths by a third among tobacco and alcohol users in Kerala, the only randomised evidence that oral cancer screening works.
Cluster-randomised trial in 13 clusters of Trivandrum district: 96,517 people in seven intervention clusters received three rounds of oral visual inspection by trained health workers and 95,356 in six control clusters received usual care. Oral cancer deaths were 77 versus 87 (mortality rate ratio 0.79; 95% CI 0.51-1.22 overall), with a significant reduction in tobacco or alcohol users (0.66; 95% CI 0.45-0.95) and in male users (0.57; 0.35-0.93). The 15-year follow-up (Oral Oncology 2013) showed a 24% mortality reduction in users after four rounds and 81% (69-89%) in users who attended all four rounds.
Targeted visual screening of tobacco and alcohol users is a cheap, workable way to cut oral cancer deaths in high-incidence countries, and is the basis for India's national oral cancer screening component. Its effect depends on people attending repeatedly and on treatment being available.
Shares Rengaswamy Sankaranarayanan, International Agency for Research on Cancer (IARC / WHO), Prevention we already have is not deployed, The hardest cancers are found late.
Shares Kerala oral cancer visual screening trial (Trivandrum), Buccal mucosa and gingivobuccal cancer (oral cancer in India), Head and neck squamous cell carcinoma.
Shares Chemoprevention & risk-reducing surgery, International Agency for Research on Cancer (IARC / WHO), Prevention we already have is not deployed, The hardest cancers are found late.
Shares Prevention we already have is not deployed, The hardest cancers are found late, Head and neck squamous cell carcinoma.
Shares Buccal mucosa and gingivobuccal cancer (oral cancer in India), Oral cavity cancer (mouth and tongue).
Shares Rengaswamy Sankaranarayanan, International Agency for Research on Cancer (IARC / WHO), Prevention we already have is not deployed, The hardest cancers are found late.
Shares International Agency for Research on Cancer (IARC / WHO), Prevention we already have is not deployed, Head and neck squamous cell carcinoma.
Shares International Agency for Research on Cancer (IARC / WHO), Prevention we already have is not deployed, Head and neck squamous cell carcinoma.