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institutionsInstitution
University Cancer Center Frankfurt (UCT)
The University Cancer Center Frankfurt, founded in 2008, is a German Cancer Aid centre of excellence; it inherits Paul Ehrlich's Georg-Speyer-Haus, where the 'magic bullet' idea behind antibody-drug conjugates was born, and its clinical strengths are acute leukaemia, CAR-T and neuro-oncology.
Also called: Universitäres Centrum für Tumorerkrankungen FrankfurtUCT Frankfurt-MarburgUniversitätsklinikum Frankfurt
Overview
The UCT was founded in 2008 at Universitätsklinikum Frankfurt and is a German Cancer Aid Oncology Center of Excellence and DKTK partner site; since 2020 it forms UCT Frankfurt-Marburg with the University Hospital Marburg. Frankfurt's Georg-Speyer-Haus, where Paul Ehrlich developed Salvarsan and the concept of targeted 'magic bullets' that underpins today's antibody-drug conjugates, is now an institute for tumour biology of the Goethe University, and the Frankfurt Cancer Institute unites basic and clinical groups. Clinical strengths include acute leukaemia and the German AML study group activities, CAR-T and stem cell transplantation, neuro-oncology and paediatric oncology. Marburg's pathology under Carsten Denkert brings the German Breast Group's translational research into the alliance.
Location
Frankfurt am Main, DE
Type
cancer center · Goethe-Universität Frankfurt
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#218 · 28 points (0 Newsweek + 0 NCI + 28 from 14 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to University Hospital Frankfurt, including child institutions. 466 works · 5,556 citations · 75% open access · 16% clinical trials · 1% reviews.
Oncology works per year
1082022
832023
952024
892025
912026
Most works
- Thorsten Oliver Goetze31 works
- Emmanouil Fokas22 works
- Peter Bader22 works
- Ralf‐Dieter Hofheinz21 works
- Markus Diefenhardt21 works
- Christine Solbach20 works
- Evelyn Ullrich20 works
- Wolf O. Bechstein19 works
- Martin Sebastian16 works
- Thomas Karn16 works
Most cited
- Acute leukaemia
- CAR-T and transplantation
- Neuro-oncology
- Frankfurt Cancer Institute
- UCT Frankfurt-Marburg
Christian Brandts
Director, UCT Frankfurt (Geschäftsführender Direktor)
Haematology and medical oncologyLeukaemiaCancer centre management
Haematologist-oncologist who is Managing Director of the University Cancer Center Frankfurt.
Florian R. Greten
Director, Georg-Speyer-Haus (Institute for Tumor Biology and Experimental Therapy)
Tumour biologyInflammation and cancerColorectal cancer
Tumour biologist known for linking inflammation to cancer, directing the Georg-Speyer-Haus within UCT Frankfurt.
Hubert Serve
Director, Department of Internal Medicine 2 (Hematology/Oncology)
Acute myeloid leukaemiaHaematologyTargeted therapy
Leukaemia specialist heading haematology and oncology at University Hospital Frankfurt and co-author of the pivotal RATIFY midostaurin trial.
Nicola Gökbuget
Head of the GMALL Study Group; Professor of Medicine, University Hospital Frankfurt
Adult acute lymphoblastic leukaemiaMeasurable residual diseaseCooperative-group trials
Leads the German GMALL group and showed blinatumomab clears residual leukaemia in adults with ALL.
Carsten Denkert
Director, Institute of Pathology, Philipps University Marburg; GBG pathology lead
Breast pathologyTumour-infiltrating lymphocytesPredictive biomarkers
Pathologist who established tumour-infiltrating lymphocytes as a biomarker in breast cancer.
Similar pages
- Key paperTumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
Shares Carsten Denkert, German Breast Group (GBG).
- InstitutionComprehensive Cancer Center Freiburg (CCCF)
Shares German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Acute myeloid leukaemia.
- InstitutionComprehensive Cancer Center Tübingen-Stuttgart
Shares German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Glioma & glioblastoma, Acute myeloid leukaemia.
- Key paperClinical and molecular characteristics of HER2-low-positive breast cancer: pooled analysis of individual patient data from four prospective, neoadjuvant clinical trials
Shares Carsten Denkert, German Breast Group (GBG).
- PersonStefan Fröhling
Shares German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ).
- InstitutionUniversity Cancer Center Mainz (UCT Mainz) / Universitätsmedizin Mainz
Shares German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), CAR-T cell therapy.
- Key paperGermline mutation status, pathological complete response, and disease-free survival in triple-negative breast cancer: secondary analysis of the GeparSixto randomized clinical trial
Shares Carsten Denkert, German Breast Group (GBG).
- TargetInterleukin-6 and IL-6 receptor
Shares Grivennikov, Greten and Karin 2010: immunity, inflammation and cancer, CAR-T cell therapy.