{"entity":{"id":"uct-frankfurt","kind":"institution","name":"University Cancer Center Frankfurt (UCT)","aka":["Universitäres Centrum für Tumorerkrankungen Frankfurt","UCT Frankfurt-Marburg","Universitätsklinikum Frankfurt"],"tldr":"The University Cancer Center Frankfurt, founded in 2008, is a German Cancer Aid centre of excellence; it inherits Paul Ehrlich's Georg-Speyer-Haus, where the 'magic bullet' idea behind antibody-drug conjugates was born, and its clinical strengths are acute leukaemia, CAR-T and neuro-oncology.","summary":"The UCT was founded in 2008 at Universitätsklinikum Frankfurt and is a German Cancer Aid Oncology Center of Excellence and DKTK partner site; since 2020 it forms UCT Frankfurt-Marburg with the University Hospital Marburg. Frankfurt's Georg-Speyer-Haus, where Paul Ehrlich developed Salvarsan and the concept of targeted 'magic bullets' that underpins today's antibody-drug conjugates, is now an institute for tumour biology of the Goethe University, and the Frankfurt Cancer Institute unites basic and clinical groups. Clinical strengths include acute leukaemia and the German AML study group activities, CAR-T and stem cell transplantation, neuro-oncology and paediatric oncology. Marburg's pathology under Carsten Denkert brings the German Breast Group's translational research into the alliance.","asOf":"2026-09-09","links":[{"label":"Homepage","url":"https://www.uct-frankfurt.de"},{"label":"Georg-Speyer-Haus","url":"https://www.georg-speyer-haus.de"},{"label":"Frankfurt Cancer Institute","url":"https://fci.health"}],"tags":[],"related":[],"cancers":["aml","glioblastoma","dlbcl","all-leukemia"],"sections":["cell-therapy","adcs"],"technologies":["car-t","adc","monoclonal-antibody"],"targets":[],"drugs":[],"companies":["gbg"],"institutions":["dkfz"],"pathways":[],"terms":[],"trials":[],"people":["carsten-denkert","christian-brandts","florian-greten","hubert-serve","nicola-gokbuget"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Frankfurt am Main","country":"DE","lat":50.094,"lng":8.657,"institutionType":"cancer-center","website":"https://www.uct-frankfurt.de","university":"Goethe-Universität Frankfurt","programs":["Acute leukaemia","CAR-T and transplantation","Neuro-oncology","Frankfurt Cancer Institute","UCT Frankfurt-Marburg"]},"route":"/institutions/uct-frankfurt/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"section":[{"id":"adcs","kind":"section","name":"Antibody-Drug Conjugates","route":"/fronts/adcs/"},{"id":"cell-therapy","kind":"section","name":"Cell Therapy","route":"/fronts/cell-therapy/"}],"technology":[{"id":"adc","kind":"technology","name":"Antibody-drug conjugate (ADC)","route":"/technologies/adc/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"}],"company":[{"id":"gbg","kind":"company","name":"German Breast Group (GBG)","route":"/companies/gbg/"}],"institution":[{"id":"dktk","kind":"institution","name":"German Cancer Consortium (DKTK)","route":"/institutions/dktk/"},{"id":"dkfz","kind":"institution","name":"German Cancer Research Center (DKFZ)","route":"/institutions/dkfz/"},{"id":"krankenhaus-nordwest","kind":"institution","name":"Krankenhaus Nordwest / Institute of Clinical Cancer Research (IKF)","route":"/institutions/krankenhaus-nordwest/"}],"person":[{"id":"carsten-denkert","kind":"person","name":"Carsten Denkert","route":"/people/carsten-denkert/"},{"id":"christian-brandts","kind":"person","name":"Christian Brandts","route":"/people/christian-brandts/"},{"id":"florian-greten","kind":"person","name":"Florian R. Greten","route":"/people/florian-greten/"},{"id":"hubert-serve","kind":"person","name":"Hubert Serve","route":"/people/hubert-serve/"},{"id":"nicola-gokbuget","kind":"person","name":"Nicola Gökbuget","route":"/people/nicola-gokbuget/"}],"paper":[{"id":"paper-grivennikov-immunity-inflammation-cancer-cell-2010","kind":"paper","name":"Grivennikov, Greten and Karin 2010: immunity, inflammation and cancer","route":"/key-papers/paper-grivennikov-immunity-inflammation-cancer-cell-2010/"}]}}