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institutionsInstitution
St. Jude Children's Research Hospital
The only NCI comprehensive cancer centre devoted to children, where Total Therapy protocols made childhood leukaemia curable; families are never billed for care.
Also called: St. Jude
Overview
Founded by Danny Thomas in 1962 and NCI comprehensive since 2008, St. Jude treats children with cancer and catastrophic diseases without charging families for treatment, travel, housing or food. Donald Pinkel's Total Therapy protocols pioneered combination chemotherapy with CNS-directed therapy in acute lymphoblastic leukaemia; by St. Jude's own figures ALL survival rose from about 4% when the hospital opened to about 94% today. The Pediatric Cancer Genome Project with Washington University (2010) sequenced hundreds of paediatric tumours, and St. Jude Cloud shares the data; the hospital opened the first proton centre dedicated to children in 2015 and runs molecularly risk-adapted trials in medulloblastoma, neuroblastoma and retinoblastoma. St. Jude Global works to raise childhood cancer survival in low- and middle-income countries, and Julie Park chairs its Department of Oncology.
Location
Memphis, TN, US
Type
cancer center
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
NCI designation
comprehensive
OnCo score
#28 · 77 points (0 Newsweek + 15 NCI + 62 from 31 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to St. Jude Children's Research Hospital, including child institutions. 636 works · 8,887 citations · 75% open access · 9% clinical trials · 2% reviews.
Oncology works per year
1162022
1562023
1282024
1472025
892026
Most works
- Stephen Gottschalk88 works
- Giedre Krenciute79 works
- Jorge Ibañez-Vega40 works
- Aimee C. Talleur37 works
- Paul G. Thomas35 works
- Jeremy Chase Crawford33 works
- Rebecca Gardner32 works
- Mireya Paulina Velasquez31 works
- Deanna Langfitt30 works
- Swati Naik27 works
Most cited
- Acute lymphoblastic leukaemia (Total Therapy)
- Pediatric Cancer Genome Project
- Proton therapy for children
- St. Jude Global
Amar Gajjar
Chair, Department of Pediatric Medicine, St. Jude Children's Research Hospital
MedulloblastomaPaediatric neuro-oncologyRisk-adapted therapy
Led the St. Jude medulloblastoma trials that introduced molecular subgroups into risk-adapted treatment.
Ching-Hon Pui
Chair, Department of Oncology, St. Jude Children's Research Hospital
Paediatric acute lymphoblastic leukaemiaRisk-adapted therapyPharmacogenomics
Led the St. Jude Total Therapy studies that cure over 90% of children with leukaemia without cranial radiation.
Giles W. Robinson
Paediatric neuro-oncologist, St. Jude Children's Research Hospital
MedulloblastomaMolecular subgroup-directed therapyPaediatric brain tumour trials
Memphis paediatric neuro-oncologist who led the study showing that the Hedgehog inhibitor vismodegib helps only adults and older children whose medulloblastoma belongs to the SHH subgroup, an early example of subgroup-directed brain tumour therapy.
James R. Downing
President and Chief Executive Officer
Paediatric leukemia genomicsHematopathologyCancer genomics
Hematopathologist and cancer genomics pioneer who has led St. Jude Children's Research Hospital since 2014.
Robbie G. Majzner
Director of Solid Tumor Immunotherapy, Department of Oncology, St. Jude Children's Research Hospital
Paediatric CAR T-cell therapySolid tumour immunotherapyGD2 and B7-H3 targets
Led the GD2 CAR-T trial in diffuse midline glioma and defined antigen density as a barrier to CAR-T in solid tumours.
Julie R. Park
Chair, Department of Oncology, St. Jude Children's Research Hospital; Children's Oncology Group neuroblastoma investigator
NeuroblastomaImmunotherapyPaediatric oncology
Julie Park led the COG trial that made tandem transplant standard for high-risk neuroblastoma.
Similar pages
- InstitutionSIOP Europe (European Society for Paediatric Oncology)
Shares WNT-activated medulloblastoma, Group 3 and group 4 medulloblastoma (non-WNT/non-SHH), SHH-activated medulloblastoma, Ependymoma.
- TrialCOG ACNS0331
Shares WNT-activated medulloblastoma, Group 3 and group 4 medulloblastoma (non-WNT/non-SHH), Childhood Cancer Survivor Study (CCSS), Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first.
- CollectionAlex's Lemonade Stand Foundation (ALSF)
Shares Retinoblastoma, Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Medulloblastoma, Osteosarcoma.
- InstitutionTexas Children's Cancer and Hematology Center
Shares Medulloblastoma, Osteosarcoma, Children's Oncology Group (COG), Neuroblastoma (paediatric).
- IdeaMake paediatric combination studies part of every relevant adult cancer drug approval
Shares Standard-risk B-cell acute lymphoblastic leukaemia in children, Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Children's Oncology Group (COG), Neuroblastoma (paediatric).
- TechnologyTeeth, jaws and facial growth after treatment in childhood
Shares Retinoblastoma, Childhood Cancer Survivor Study (CCSS), Medulloblastoma, Children's Oncology Group (COG).
- CollectionSt. Baldrick's Foundation
Shares Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Medulloblastoma, Osteosarcoma, Children's Oncology Group (COG).
- TrialCOG ANBL0032
Shares Julie R. Park, Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Children's Oncology Group (COG), Neuroblastoma (paediatric).
cancers
Acute lymphoblastic leukaemiaAcute myeloid leukaemia in childrenAtypical teratoid/rhabdoid tumour (ATRT)CraniopharyngiomaEpendymomaGroup 3 and group 4 medulloblastoma (non-WNT/non-SHH)MedulloblastomaNeuroblastoma (paediatric)OsteosarcomaPhiladelphia chromosome-like acute lymphoblastic leukaemia (Ph-like or BCR::ABL1-like ALL)RetinoblastomaSHH-activated medulloblastomaStandard-risk B-cell acute lymphoblastic leukaemia in childrenWNT-activated medulloblastoma
technologies
companies
institutions
trials
roadmaps
ideas
collections
people
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key papers
Open-source projects
All open source in oncology →Open-source projects that this organisation maintains, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
St. Jude's visualisation platform for paediatric cancer genomics behind the St. Jude Cloud and PeCan portals.