A childhood-cancer charity started by a four-year-old patient's lemonade stand that now funds hundreds of grants and runs an open-science data lab for paediatric cancer genomics.
Founded 2005 after Alexandra Scott's fundraising (she died of neuroblastoma in 2004 at age 8). ALSF has awarded >$300 million in grants, runs the Childhood Cancer Data Lab (Philadelphia) whose refine.bio harmonises public transcriptomic data and whose OpenPBTA/OpenPedCan atlas underpins paediatric brain tumour research, funds the Crazy 8 initiative for the hardest paediatric cancers, and supports families' travel to treatment. Partner of the Children's Oncology Group and CHOP.
Shares Rhabdomyosarcoma, Wilms tumour (nephroblastoma), Ewing sarcoma, Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first and the tags patient-org, paediatric.
Shares Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Neuroblastoma (paediatric), Acute lymphoblastic leukaemia and the tag paediatric.
Shares Retinoblastoma, Rhabdomyosarcoma, Medulloblastoma, Children's Oncology Group (COG) and the tag paediatric.
Shares Rhabdomyosarcoma, Wilms tumour (nephroblastoma), Ewing sarcoma, Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first and the tag paediatric.
Shares Medulloblastoma and the tag patient-org.
Shares Acute lymphoblastic leukaemia and the tag patient-org.
Shares Hepatoblastoma, Rhabdomyosarcoma, Wilms tumour (nephroblastoma), Children's Oncology Group (COG) and the tag paediatric.
Shares Wilms tumour (nephroblastoma), Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first, Children's Oncology Group (COG) and the tag paediatric.
Open-source projects that are the code behind this collection or publish it, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
Alex's Lemonade Stand Foundation's harmonised, ready-to-use collection of public gene expression data.
The Open Pediatric Brain Tumor Atlas: a fully open, collaboratively written set of analyses of the CBTN paediatric brain tumour cohort, where every module was reviewed in public.
Open, community analysis of the Single-cell Pediatric Cancer Atlas, run in the same open-review model as OpenPBTA.