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institutionsInstitution
Centre Léon Bérard
Lyon's cancer centre, a world reference for sarcoma and rare cancers, led by Jean-Yves Blay, who also presides over UNICANCER.
Also called: CLBCentre de Lutte Contre le Cancer de Lyon
Overview
Founded in 1923, the Centre Léon Bérard is the UNICANCER centre for the Auvergne-Rhône-Alpes region and the clinical arm of the Cancer Research Center of Lyon (CRCL, with Inserm, CNRS and Lyon 1). Under Jean-Yves Blay it coordinates the French NetSarc sarcoma network and the European Reference Network for rare adult solid cancers (EURACAN). Programmes include the ProfiLER molecular profiling study, a large early-phase unit, breast oncology under Thomas Bachelot, paediatric oncology (IHOPe) and a Lyon Integrated Cancer Research Site (LYriCAN). The International Agency for Research on Cancer sits in the same city.
Location
Lyon, FR
Type
cancer center · Université Claude Bernard Lyon 1
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#256 · 24 points (0 Newsweek + 0 NCI + 24 from 12 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-10-01.
Matched to Centre Léon Bérard, including child institutions. 1,061 works · 14,344 citations · 72% open access · 17% clinical trials · 1% reviews.
Oncology works per year
2012022
2512023
2182024
2282025
1632026
Most works
- Isabelle Ray-Coquard87 works
- Olivier Trédan82 works
- Philippe Alexandre Cassier56 works
- Jean‐Yves Blay55 works
- Maurice Pérol54 works
- Éric Pujade-Lauraine52 works
- Stéphane Dalle48 works
- Christelle de la Fouchardière43 works
- Ignace B. Vergote39 works
- Olivia Pérol35 works
Most cited
- Sarcoma and rare cancers (NetSarc, EURACAN)
- ProfiLER precision oncology
- Early-phase trials
- Breast oncology
- Paediatric oncology (IHOPe)
Isabelle Ray-Coquard
Professor of Medical Oncology, Centre Léon Bérard and Université Claude Bernard Lyon 1; President, GINECO
Ovarian cancerRare gynaecological tumoursPARP inhibitor combinations
Led PAOLA-1, which showed olaparib plus bevacizumab helps women with HRD-positive ovarian cancer beyond BRCA carriers.
Patrick Mehlen
Director of Fundamental and Translational Research and of the Cancer Research Center of Lyon (CRCL)
Cancer cell biologyDependence receptorsNetrin-1
Cancer biologist who discovered the dependence-receptor concept and took netrin-1 blockade from bench to clinical trials at Centre Léon Bérard.
Jean-Yves Blay
Director General, Centre Léon Bérard, Lyon; President, UNICANCER
SarcomaGISTRare cancers
Sarcoma expert who leads Centre Léon Bérard and the French cancer centre network UNICANCER.
Thomas Bachelot
Head of Medical Oncology, Centre Léon Bérard, Lyon
Breast cancerBrain metastasesEndocrine therapy
Breast oncologist who led UNICANCER trials on brain metastases and hormone therapy resistance.
Similar pages
- IdeaGrow immune command posts inside tumours
Shares Jean-Yves Blay, Sarcomas (soft tissue, bone, GIST), Melanoma, Immune checkpoint inhibitors.
- InstitutionInstitut Bergonié
Shares UNICANCER, Rare and paediatric cancers without markets, Comprehensive genomic profiling, Sarcomas (soft tissue, bone, GIST).
- TrialCABONE
Shares French Sarcoma Group, Sarcomas (soft tissue, bone, GIST), Small-molecule kinase inhibitors.
- IdeaOne standing umbrella trial for all rare cancers in a country
Shares UNICANCER, Rare and paediatric cancers without markets, Comprehensive genomic profiling, Sarcomas (soft tissue, bone, GIST).
- IdeaLet adolescents from age 12 into adult trials when the cancer biology is the same
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- IdeaA same-week expert second opinion for every rare cancer diagnosis
Shares Jean-Yves Blay, Rare and paediatric cancers without markets, Sarcomas (soft tissue, bone, GIST).
- InstitutionGeneva University Hospitals (HUG)
Shares International Agency for Research on Cancer (IARC / WHO), Melanoma, HR-positive / HER2-negative breast cancer, Immune checkpoint inhibitors.
- TrialANGIOTAX
Shares French Sarcoma Group, Sarcomas (soft tissue, bone, GIST).