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Seven in ten cancer deaths are in poorer countries, yet almost all trials happen in rich ones. Funders would commit a share of money for trials designed and led where the burden is.
The largest cancer research funders commit a fixed fraction (say 15%) of their trials budget to studies whose principal investigator and majority of sites are in low- and middle-income countries, targeting cancers and questions that matter there: cervical cancer treatment with limited radiotherapy, oesophageal squamous cell carcinoma, hepatocellular carcinoma from hepatitis B, hypofractionation and shorter regimens, low-cost generics. Precedents include Tata Memorial's trials that changed global practice on low-dose immunotherapy and neoadjuvant chemotherapy in head and neck cancer at a fraction of Western trial costs.
Shares Carlos Barrios, Sudeep Gupta, Tata Memorial Centre, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation.
Shares Tata Memorial Centre, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Most of the world has almost no cancer care, Cervical cancer.
Shares Tata Memorial Centre, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Most of the world has almost no cancer care, Cervical cancer.
Shares Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Most of the world has almost no cancer care, Oesophageal cancer, Cervical cancer.
Shares Hospital Israelita Albert Einstein, Carlos Barrios, Most of the world has almost no cancer care.
Shares Rajendra Badwe, Sudeep Gupta, Tata Memorial Centre, Cervical cancer.
Shares Benefits of hyperthermic intraperitoneal chemotherapy for patients with serosal invasion in gastric cancer: a meta-analysis of the randomized controlled trials, Trials do not represent the people who get cancer, Funding follows fashion, not burden.
Shares Tata Memorial Centre, Most of the world has almost no cancer care, Oesophageal cancer, Cervical cancer.