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RC118-ADC is an experimental antibody-drug conjugate from RemeGen in phase 2 trials, aimed at Claudin 18.2.
RC118-ADC (RC118) is an antibody-drug conjugate developed by RemeGen. Its target is Claudin 18.2 (the sponsor names Claudin 18.2). The sponsor states: An antibody-drug conjugate combining a Claudin 18.2-targeting antibody with a microtubule inhibitor payload. ClinicalTrials.gov describes the intervention as: RC118 for injection is a novel antibody-drug conjugate, with a Claudin 18.2-targeting antibody and a microtube inhibitor. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial. The largest, NCT05205850, plans to enrol 135 participants with primary completion was scheduled for 2025-09-30 on the registry. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
An antibody-drug conjugate combining a Claudin 18.2-targeting antibody with a microtubule inhibitor payload. Connects to Claudin 18.2.
1.RC118-ADC's antibody arm binds Claudin 18.2 on the surface of the cancer cell.
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Query for this drug: (TITLE:"RC118-ADC" OR ABSTRACT:"RC118-ADC" OR TITLE:"RC118" OR ABSTRACT:"RC118" OR TITLE:"RC118 for injection" OR ABSTRACT:"RC118 for injection") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about RC118-ADC, not a curated reading list.
Shares A Study of RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors, RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares RemeGen and the tag pipeline.
Shares Claudin 18.2 and the tag pipeline.