Loading
Lipiodol is an iodine-rich oil injected into the liver's artery that lodges in liver tumours; it lets radiologists see them on CT and is the vehicle that carries chemotherapy into the tumour in conventional chemoembolisation for liver cancer.
Ethiodized oil has been approved in the United States since 1954, originally for lymphangiography and hysterosalpingography. In 2014 the FDA added selective hepatic intra-arterial use for imaging tumours in adults with known hepatocellular carcinoma, formalising its decades-old role in conventional transarterial chemoembolisation, where it is emulsified with doxorubicin or cisplatin and injected before the feeding vessels are blocked. The oil is also the carrier for iodine-131 lipiodol and for imaging hepatocellular carcinoma nodules on follow-up CT. Guerbet manufactures it.
An iodinated poppy-seed oil that is retained selectively by hepatocellular carcinoma after hepatic arterial injection, both showing the tumour on CT and carrying chemotherapy into it during chemoembolisation.
1.Ethiodized oil slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1954 | Lymphangiography and hysterosalpingography; selective hepatic intra-arterial imaging of hepatocellular carcinoma added in 2014 |
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Query for this drug: (TITLE:"Ethiodized oil" OR ABSTRACT:"Ethiodized oil" OR TITLE:"Lipiodol" OR ABSTRACT:"Lipiodol" OR TITLE:"Ethiodol" OR ABSTRACT:"Ethiodol" OR TITLE:"Iodised poppy-seed oil" OR ABSTRACT:"Iodised poppy-seed oil") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Ethiodized oil, not a curated reading list.
Shares Doxorubicin and the tag chembl-universe.
Shares Doxorubicin and the tag chembl-universe.
Shares Doxorubicin and the tag chembl-universe.
Shares Hepatocellular carcinoma and the tag chembl-universe.
Shares Transarterial Chemoembolization Compared With Stereotactic Body Radiation Therapy or Stereotactic Ablative Radiation Therapy in Treating Patients With Residual or Recurrent Liver Cancer Undergone Initial Transarterial Chemoembolization, Endovascular Brachytherapy Combined With Stent Placement and TACE for HCC With Main Portal Vein Tumor Thrombus, Liver Resection Versus Transarterial Chemoembolization for the Treatment of Intermediate-stage Hepatocellular Carcinoma, Transarterial chemoembolisation (TACE).
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.