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Injecting tiny radioactive glass or resin beads into the liver's artery so they lodge in the tumour and irradiate it from inside.
Yttrium-90 microspheres (20-60 µm) deliver beta radiation over a few millimetres with a 64-hour half-life, treating hepatocellular carcinoma, colorectal liver metastases and neuroendocrine liver metastases. Randomised trials against sorafenib (SARAH, SIRveNIB) showed no survival gain but better tolerability; radiation segmentectomy, which delivers ablative doses to a small segment, achieves outcomes close to ablation. Dosimetry now individualises the activity (DOSISPHERE). Chosen over TACE when portal vein thrombus is present.
Shares TACE (transarterial chemoembolisation), Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Portal vein tumour thrombus (macrovascular invasion), TACE (transarterial chemoembolisation), Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma.
Shares Portal vein tumour thrombus (macrovascular invasion), Hepatocellular carcinoma.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma, Colorectal cancer.
Shares Transarterial chemoembolisation (TACE), Hepatocellular carcinoma, Colorectal cancer.
Shares Liver-directed therapy (TACE, TARE, HAI, ablation), Hepatocellular carcinoma, Colorectal cancer.