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Trials
A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer.

trialsTrialRecruiting

A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer.

A phase 2/3 trial of tirapazamine in hepatocellular carcinoma, run by Zhejiang Raygene Pharmaceuticals Co., Ltd, now recruiting.

Overview Connected3

Overview

A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer. is a phase 2/3 interventional study registered as NCT06844357 by Zhejiang Raygene Pharmaceuticals Co., Ltd, with 300 participants planned, started 2025-03-27 and due to reach its primary completion in 2029-04-01. Interventions recorded: tirapazamine, Transarterial Embolization (TAE) and TACE.

Setting

A Multi-center, Randomized, Controlled, Open-label Phase II/III Clinical Trial to Investigate Whether Transarterial Tirapazamine Injection Followed by Transarterial Embolization (TATE) is Superior to Traditional Transarterial Chemoembolization (TACE) in Patients With Intermediate-Stage Hepatocellular Carcinoma (HCC)

Phase

Phase 2/3

Sponsor

Zhejiang Raygene Pharmaceuticals Co., Ltd

Registry

Started

2025-03-27

Enrolled

300 enrolled

Connected

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cancers

Hepatocellular carcinoma Intermediate hepatocellular carcinoma (BCLC B)

technologies

Transarterial chemoembolisation (TACE)

Evidence strength34/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2/3+22
300 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT06844357

Data

JSON ·

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Cancers

Hepatocellular carcinoma
Intermediate hepatocellular carcinoma (BCLC B)

Technologies

Transarterial chemoembolisation (TACE)

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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