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Trials
Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC

trialsTrialRecruiting

Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC

A phase 1/2 trial of Ori-C101 in hepatocellular carcinoma, run by OriCell Therapeutics Co., Ltd., now recruiting.

Also called: BEACON

Overview Connected2

Overview

Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC is a phase 1/2 interventional study registered as NCT05652920 by OriCell Therapeutics Co., Ltd., with 105 participants planned, started 2022-12-15 and due to reach its primary completion in 2026-12. Interventions recorded: Ori-C101.

Setting

A Phase Ib/II, Open-Label, Multi-Center Study to Investigate the Safety, PK, and Efficacy of Ori-C101 in Advanced Hepatocellular Carcinoma (HCC) Patients (BEACON)

Phase

Phase 1/2

Sponsor

OriCell Therapeutics Co., Ltd.

Registry

Started

2022-12-15

Enrolled

105 enrolled

Connected

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cancers

Advanced hepatocellular carcinoma (BCLC C)Hepatocellular carcinoma

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
105 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT05652920

Data

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Cancers

Hepatocellular carcinoma
Advanced hepatocellular carcinoma (BCLC C)

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