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Trials
A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and Pimitespib

trialsTrialRecruiting

A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and Pimitespib

A phase 2 trial of Velzatinib in advanced solid tumours, run by GlaxoSmithKline, now recruiting.

Also called: StrateGIST J

Overview Connected3

Overview

A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and Pimitespib is a phase 2 interventional study registered as NCT07689201 by GlaxoSmithKline, with 24 participants planned, started 2026-08-17 and due to reach its primary completion in 2027-11-29. Interventions recorded: Velzatinib.

Setting

A Phase 2, Single-arm, Multicenter, Open-Label Study of Velzatinib (GSK6042981) in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (GIST) After Imatinib, Sunitinib, Regorafenib, and Pimitespib Therapies (StrateGIST J)

Phase

Phase 2

Sponsor

GlaxoSmithKline

Registry

Started

2026-08-17

Enrolled

24 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 3not stated (registered as a drug or biological on ClinicalTrials.gov)

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
24 enrolled+7
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT07689201

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

Velzatinib

Companies

GSK

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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