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Trials
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

trialsTrialRecruiting

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

A phase 1/2 trial of AZD4512 in acute lymphoblastic leukaemia, run by AstraZeneca, now recruiting.

Also called: ALLight

Overview Connected4

Overview

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia is a phase 1/2 interventional study registered as NCT07109219 by AstraZeneca, with 83 participants planned, started 2025-11-12 and due to reach its primary completion in 2028-04-28. Interventions recorded: AZD4512 monotherapy.

Setting

A Modular Phase I/II, Open-label, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of AZD4512 Monotherapy or in Combination With Anticancer Agent(s) in Participants With Acute Lymphoblastic Leukemia

Phase

Phase 1/2

Sponsor

AstraZeneca

Registry

Started

2025-11-12

Enrolled

83 enrolled

Connected

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cancers

Acute lymphoblastic leukaemia

drugs

Phase 2ADC

companies

AstraZeneca Fortrea

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
83 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT07109219

Data

JSON ·

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Cancers

Acute lymphoblastic leukaemia

Products

AZD4512

Companies

AstraZeneca
Fortrea

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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