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Trials
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

trialsTrialRecruiting

AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

A phase 1/2 trial of Surovatamig in acute lymphoblastic leukaemia, run by AstraZeneca, now recruiting.

Also called: SYRUS

Overview Connected2

Overview

AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia is a phase 1/2 interventional study registered as NCT06137118 by AstraZeneca, with 255 participants planned, started 2023-12-29 and due to reach its primary completion in 2028-02-11. Interventions recorded: Surovatamig.

Setting

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AZD0486 in Adolescent and Adult Participants With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukaemia

Phase

Phase 1/2

Sponsor

AstraZeneca

Registry

Started

2023-12-29

Enrolled

255 enrolled

Connected

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cancers

Acute lymphoblastic leukaemia

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
255 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT06137118

Data

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Cancers

Acute lymphoblastic leukaemia

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AstraZeneca

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