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Trials
A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients

trialsTrialRecruiting

A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients

A phase 3 trial of CAR T cells in gastric & gastro-oesophageal junction cancer, run by Suzhou Immunofoco Biotechnology Co., Ltd, now recruiting.

Overview Connected3

Overview

A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients is a phase 3 interventional study registered as NCT07103668 by Suzhou Immunofoco Biotechnology Co., Ltd, with 150 participants planned, started 2025-08-06 and due to reach its primary completion in 2027-05-31. Interventions recorded: CAR T cells and Control.

Setting

An Open-label, Randomized, Comparative Phase III Study Including Patients With CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer.

Phase

Phase 3

Sponsor

Suzhou Immunofoco Biotechnology Co., Ltd

Registry

Started

2025-08-06

Enrolled

150 enrolled

Connected

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cancers

Claudin 18.2-positive gastric cancer Gastric & gastro-oesophageal junction cancer

technologies

CAR-T cell therapy

Evidence strength41/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 3+30
150 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT07103668

Data

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Cancers

Gastric & gastro-oesophageal junction cancer
Claudin 18.2-positive gastric cancer

Technologies

CAR-T cell therapy

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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