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Trials
A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors

trialsTrialRecruiting

A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors

A phase 2 trial of Denosumab in advanced solid tumours, run by Suzhou Suncadia Biopharmaceuticals Co., Ltd., now recruiting.

Overview Connected5

Overview

A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors is a phase 2 interventional study registered as NCT07028268 by Suzhou Suncadia Biopharmaceuticals Co., Ltd., with 210 participants planned, started 2025-06-24 and due to reach its primary completion in 2025-12. Interventions recorded: SHR-2017、Denosumab placebo and Denosumab；SHR-2017 placebo.

Setting

A Multicenter, Randomized, Double-Blind, Positively Controlled Phase II Clinical Study Evaluating the Efficacy and Safety of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors

Phase

Phase 2

Sponsor

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Registry

Started

2025-06-24

Enrolled

210 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Bone-modifying agents (bisphosphonates, denosumab)Monoclonal antibodies

drugs

ApprovedMonoclonal antibody (anti-RANKL, fully human IgG2)

Denosumab · Xgeva / Prolia

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
210 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07028268

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Bone-modifying agents (bisphosphonates, denosumab)
Monoclonal antibodies

Products

Denosumab

Companies

Jiangsu Hengrui Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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