{"entity":{"id":"nct07028268","kind":"trial","name":"A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors","aka":[],"tldr":"A phase 2 trial of Denosumab in advanced solid tumours, run by Suzhou Suncadia Biopharmaceuticals Co., Ltd., now recruiting.","summary":"A Trial of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors is a phase 2 interventional study registered as NCT07028268 by Suzhou Suncadia Biopharmaceuticals Co., Ltd., with 210 participants planned, started 2025-06-24 and due to reach its primary completion in 2025-12. Interventions recorded: SHR-2017、Denosumab placebo and Denosumab；SHR-2017 placebo.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07028268","url":"https://clinicaltrials.gov/study/NCT07028268"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":["bone-modifying-agents","monoclonal-antibody"],"targets":[],"drugs":["denosumab"],"companies":["hengrui"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07028268","phase":"2","setting":"A Multicenter, Randomized, Double-Blind, Positively Controlled Phase II Clinical Study Evaluating the Efficacy and Safety of SHR-2017 Injection in Patients With Bone Metastases From Solid Tumors","sponsor":"Suzhou Suncadia Biopharmaceuticals Co., Ltd.","started":"2025-06-24","startedType":"actual","enrolled":210,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07028268/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"technology":[{"id":"bone-modifying-agents","kind":"technology","name":"Bone-modifying agents (bisphosphonates, denosumab)","route":"/technologies/bone-modifying-agents/"},{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"}],"drug":[{"id":"denosumab","kind":"drug","name":"Denosumab","route":"/drugs/denosumab/"}],"company":[{"id":"hengrui","kind":"company","name":"Jiangsu Hengrui Pharmaceuticals","route":"/companies/hengrui/"}]}}