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Trials
A Phase II Clinical Study of HRS-7058 in Combination With Antitumor Drugs in Patients With Advanced Malignant Tumour

trialsTrialRecruiting

A Phase II Clinical Study of HRS-7058 in Combination With Antitumor Drugs in Patients With Advanced Malignant Tumour

A phase 2 trial of Adebrelimab, Cetuximab and SHR-A2102 in advanced solid tumours, run by Shandong Suncadia Medicine Co., Ltd., now recruiting.

Overview Connected5

Overview

A Phase II Clinical Study of HRS-7058 in Combination With Antitumor Drugs in Patients With Advanced Malignant Tumour is a phase 2 interventional study registered as NCT06915142 by Shandong Suncadia Medicine Co., Ltd., with 300 participants planned, started 2025-04-28 and due to reach its primary completion in 2026-12. Interventions recorded: HRS-7058 + SHR-1316, HRS-7058 + SHR-1316 + Platinum-containing doublet chemotherapy, HRS-7058 + Cetuximab, HRS-7058 + SHR-1826, HRS-7058 + SHR-1826 + SHR-1316 and HRS-7058 + SHR-A1202.

Setting

An Phase II Clinical Study on the Safety, Tolerability and Efficacy of HRS-7058 in Combination With Antitumor Drugs in Subjects With Solid Tumors

Phase

Phase 2

Sponsor

Shandong Suncadia Medicine Co., Ltd.

Registry

Started

2025-04-28

Enrolled

300 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedMonoclonal antibody (anti-PD-L1, humanised IgG4)

Adebrelimab · Arelili

ApprovedMonoclonal antibody (anti-EGFR)

Cetuximab · Erbitux

Phase 3antibody-drug conjugate (ADC), per the sponsor's pipeline page; form not stated in the registry record

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
300 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06915142

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

Adebrelimab
Cetuximab
SHR-A2102

Companies

Jiangsu Hengrui Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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