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Trials
A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma

trialsTrialRecruiting

A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma

A phase 1/2 trial of SHR-A2102, Adebrelimab and SHR-8068 in bladder & urothelial cancer, run by Shanghai Hengrui Pharmaceutical Co., Ltd., now recruiting.

Overview Connected6

Overview

A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma is a phase 1/2 interventional study registered as NCT06639347 by Shanghai Hengrui Pharmaceutical Co., Ltd., with 90 participants planned, started 2024-11-04 and due to reach its primary completion in 2027-05-31. Interventions recorded: SHR-A2102, Adebrelimab injection and SHR-8068 injection.

Setting

An Open Label, Multicenter, Phase Ib/Il Study to Evaluate the Safety, Tolerability, and Efficacy of SHR A2102 in Combination With Other Anti-cancer Agents in Patients With Advanced Urothelial Carcinoma

Phase

Phase 1/2

Sponsor

Shanghai Hengrui Pharmaceutical Co., Ltd.

Registry

Started

2024-11-04

Enrolled

90 enrolled

Connected

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cancers

Bladder & urothelial cancer Muscle-invasive and advanced bladder cancer

drugs

ApprovedMonoclonal antibody (anti-PD-L1, humanised IgG4)

Adebrelimab · Arelili

Phase 3monoclonal antibody (anti-CTLA-4, per the sponsor's pipeline page; form not stated in the registry record)

Phase 3antibody-drug conjugate (ADC), per the sponsor's pipeline page; form not stated in the registry record

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength23/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
90 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT06639347

Data

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Cancers

Bladder & urothelial cancer
Muscle-invasive and advanced bladder cancer

Products

SHR-A2102
Adebrelimab
SHR-8068

Companies

Jiangsu Hengrui Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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