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Trials
A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors

trialsTrialRecruiting

A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors

A phase 2 trial of SHR-A2102, Bevacizumab and Osimertinib in advanced solid tumours, run by Shanghai Hengrui Pharmaceutical Co., Ltd., now recruiting.

Overview Connected5

Overview

A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors is a phase 2 interventional study registered as NCT06895928 by Shanghai Hengrui Pharmaceutical Co., Ltd., with 400 participants planned, started 2025-03-28 and due to reach its primary completion in 2028-12. Interventions recorded: SHR-A2102, Bevacizumab Injection, Adebelimab Injection, Ametinib Mesylate Tablets and Osimertinib Mesylate Tablets.

Setting

A Phase II, Multicenter, Open-Label Study of Safety, Tolerability and Efficacy of SHR-A2102 for Injection in Combination With Other Antitumor Therapies in Patients With Advanced Solid Tumors

Phase

Phase 2

Sponsor

Shanghai Hengrui Pharmaceutical Co., Ltd.

Registry

Started

2025-03-28

Enrolled

400 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedMonoclonal antibody (anti-VEGF)

Bevacizumab · Avastin (and biosimilars)

ApprovedSmall-molecule kinase inhibitor (EGFR)

Osimertinib · Tagrisso

Phase 3antibody-drug conjugate (ADC), per the sponsor's pipeline page; form not stated in the registry record

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength33/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
400 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06895928

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

SHR-A2102
Bevacizumab
Osimertinib

Companies

Jiangsu Hengrui Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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