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Trials
Ixovex-1 Single Agent and Combination Therapy

trialsTrialRecruiting

Ixovex-1 Single Agent and Combination Therapy

A phase 1/2 trial of Pembrolizumab in head and neck squamous cell carcinoma, run by Psivac Ltd, now recruiting.

Also called: IXACT

Overview Connected4

Overview

Ixovex-1 Single Agent and Combination Therapy is a phase 1/2 interventional study registered as NCT06549946 by Psivac Ltd, with 18 participants planned, started 2024-12-17 and due to reach its primary completion in 2027-01-30. Interventions recorded: Ixovex-1 and Pembrolizumab.

Setting

A Phase I/II Open-label, Clinical Trial of Intratumoural Ixovex-1 as Single Agent Therapy or in Combination With Pembrolizumab in Palpable Solid Tumours

Phase

Phase 1/2

Sponsor

Psivac Ltd

Registry

Started

2024-12-17

Enrolled

18 enrolled

Connected

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cancers

Head and neck squamous cell carcinoma

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Pembrolizumab · Keytruda / Keytruda Qlex (SC)

companies

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
18 enrolled+6
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT06549946

Data

JSON ·

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Cancers

Head and neck squamous cell carcinoma

Technologies

Immune checkpoint inhibitors

Products

Pembrolizumab

Companies

IQVIA

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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