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Trials
Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

trialsTrialRecruiting

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

A phase 1/2 trial of REM-422 in salivary gland cancers, run by Remix Therapeutics, now recruiting.

Overview Connected4

Overview

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma is a phase 1/2 interventional study registered as NCT06118086 by Remix Therapeutics, with 125 participants planned, started 2023-12-20 and due to reach its primary completion in 2027-09-30. Interventions recorded: REM-422.

Setting

A Phase 1/2, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

Phase

Phase 1/2

Sponsor

Remix Therapeutics

Registry

Started

2023-12-20

Enrolled

125 enrolled

Connected

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cancers

Adenoid cystic carcinoma Salivary gland cancers

drugs

Phase 2Small-molecule inhibitor

companies

Remix Therapeutics

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
125 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Head and neck cancers by HPV status and site · diff · file

Sources & links

ClinicalTrials.gov NCT06118086

Data

JSON ·

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Cancers

Salivary gland cancers
Adenoid cystic carcinoma

Products

REM-422

Companies

Remix Therapeutics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

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