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Trials
A Clinical Study of MK-1045 (CN201) in People With Precursor B-cell Acute Lymphoblastic Leukemia (MK-1045-002)

trialsTrialRecruiting

A Clinical Study of MK-1045 (CN201) in People With Precursor B-cell Acute Lymphoblastic Leukemia (MK-1045-002)

A phase 1/2 trial of MK-1045 in acute lymphoblastic leukaemia, run by MSD R&D (China) Co., Ltd., now recruiting.

Overview Connected3

Overview

A Clinical Study of MK-1045 (CN201) in People With Precursor B-cell Acute Lymphoblastic Leukemia (MK-1045-002) is a phase 1/2 interventional study registered as NCT05579132 by MSD R&D (China) Co., Ltd., with 203 participants planned, started 2022-11-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: MK-1045.

Setting

An Open-label, Multi-center Phase Ib/II Study of MK-1045 (CN201) in Subjects With Precursor B-cell Acute Lymphoblastic Leukemia

Phase

Phase 1/2

Sponsor

MSD R&D (China) Co., Ltd.

Registry

Started

2022-11-01

Enrolled

203 enrolled

Connected

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cancers

Acute lymphoblastic leukaemia

drugs

Phase 3bispecific antibody (CD3 x CD19, per the sponsor's description; form not stated in the registry record)

companies

Merck & Co. (MSD)

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
203 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT05579132

Data

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Cancers

Acute lymphoblastic leukaemia

Products

MK-1045

Companies

Merck & Co. (MSD)

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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