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Treatment given after the first treatment has failed or the cancer has come back, aiming to rescue the situation. It can still be curative (salvage surgery after organ-preservation fails) or a later line of palliation.
Salvage surgery removes the organ when chemoradiation or watch-and-wait fails (laryngectomy, cystectomy, abdominoperineal resection, TME after regrowth). Salvage radiotherapy treats a rising PSA after prostatectomy; salvage chemotherapy (ICE, DHAP, GDP) followed by autologous transplant was the standard for relapsed lymphoma until CAR-T proved superior in second line (ZUMA-7, TRANSFORM). Organ-preservation strategies are only safe where salvage is feasible and centres have the surgical capacity to deliver it.
Shares RAVES (TROG 08.03/ANZUP), SWOG 8794, ARTISTIC meta-analysis, GETUG-AFU 16.
Shares RAVES (TROG 08.03/ANZUP), SWOG 8794, ARTISTIC meta-analysis, GETUG-AFU 16.
Shares SWOG 8794, ARTISTIC meta-analysis, RADICALS-RT.
Shares TRANSFORM, Autologous stem cell transplant (ASCT), ZUMA-7, Stem cell transplant in lymphoma: what it is still for.
Shares RAVES (TROG 08.03/ANZUP), SWOG 8794, ARTISTIC meta-analysis, GETUG-AFU 16.
Shares Bridging therapy, TRANSFORM, Autologous stem cell transplant (ASCT), ZUMA-7.
Shares Bridging therapy, TRANSFORM, ZUMA-7.
Shares Bridging therapy, TRANSFORM, ZUMA-7.