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How many times more radiation a cell without oxygen needs to be killed compared with the same cell with oxygen: about 2.5 to 3 for X-rays, close to 1 for the heaviest particle beams.
Oxygen reacts with the free radicals radiation creates in DNA and makes the damage permanent, so oxygenated cells die at lower doses. The oxygen enhancement ratio is near 3 for photons and protons and falls toward 1 for high-LET radiation such as carbon ions and neutrons, which is one argument for particle therapy in hypoxic tumours and for boron neutron capture therapy.
Showing the technology this term belongs to: Tumour hypoxia: imaging and modification.
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET), Carbon-ion therapy and the tag radiation-wave1.
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET), Carbon-ion therapy and the tag radiation-wave1.
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET) and the tag radiation-wave1.
Shares Tumour hypoxia: imaging and modification and the tag radiation-wave1.
Shares Relative biological effectiveness (RBE) and the tag radiation-wave1.
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET).
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET).
Shares Relative biological effectiveness (RBE), Linear energy transfer (LET), Carbon-ion therapy.