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How long a tumour stays shrunk once it has responded to a drug. A response that lasts two years is worth far more than one that lasts two months, so this is reported alongside response rate.
Measured from the first documented response to progression or death, and usually reported as a median plus the proportion of responders still responding at 6, 12 or 24 months. Immunotherapy's signature is not a high response rate but a long duration of response, with responses lasting years in a subset; conversely, many chemotherapy responses are brisk but short. Regulators weigh response rate and durability together when granting accelerated approval on single-arm data, and the durable-response tail is what turns survival curves into a plateau.
Shares Partial response, Complete response, Objective response rate (ORR).
Shares Partial response, Complete response, Progression-free survival (PFS).
Shares Objective response rate (ORR), Accelerated approval, Progression-free survival (PFS).
Shares Partial response, Complete response.
Shares Objective response rate (ORR), Progression-free survival (PFS).
Shares Partial response, Complete response, Progression-free survival (PFS).
Shares Accelerated approval, Progression-free survival (PFS).
Shares Objective response rate (ORR), Accelerated approval, Progression-free survival (PFS).