Cancer cells that fill the lining layer where they started but have not broken through the basement membrane into the tissue beneath. They cannot spread yet, so removal is usually curative; it is 'stage 0'.
Staged as Tis, in situ disease is found in breast (ductal and lobular), bladder (flat CIS, which is aggressive and treated with BCG), cervix (CIN 3), skin (Bowen's disease, melanoma in situ), oesophagus and lung (adenocarcinoma in situ). Whether and how fast it would have progressed is often unknowable, which raises overdiagnosis questions in screening. Treatment is local (excision, ablation, intravesical therapy) without systemic chemotherapy, sometimes with radiotherapy or endocrine therapy for breast DCIS.
Renal cell carcinoma comes from the kidney's filtering cortex, urothelial cancer from the lining of the collecting system and bladder, and the adrenal on top hosts cortical and medullary (neuroblastoma) tumours.
Same organ: Collecting duct carcinoma of the kidney, Renal medullary carcinoma (SMARCB1-deficient), TFE3-rearranged (translocation) renal cell carcinoma, Fumarate hydratase-deficient renal cell carcinoma (HLRCC-associated), Succinate dehydrogenase-deficient renal cell carcinoma, Mucinous tubular and spindle cell carcinoma of the kidney, Eosinophilic solid and cystic renal cell carcinoma, Clear cell papillary renal cell tumour, Urothelial carcinoma of the urethra, Squamous cell carcinoma of the urethra, Adenocarcinoma of the urethra (including clear cell adenocarcinoma), Melanoma of the urethra, Non-muscle-invasive bladder cancer, Muscle-invasive and advanced bladder cancer, Clear cell renal cell carcinoma, Papillary renal cell carcinoma, Chromophobe renal cell carcinoma, Renal cell carcinoma, Wilms tumour (nephroblastoma), Neuroblastoma (paediatric), Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma, Adrenocortical carcinoma, Pheochromocytoma and paraganglioma (PPGL), Urethral cancer, Penile cancer, Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer, Localised adrenocortical carcinoma (ENSAT stage I to III, resectable), Advanced and metastatic adrenocortical carcinoma (ENSAT stage IV or unresectable), Hereditary pheochromocytoma and paraganglioma (SDHx, VHL, RET, NF1, MAX and TMEM127), Metastatic pheochromocytoma and paraganglioma
Showing the organ this term concerns: Bladder & urothelial cancer.
Shares Actinic keratosis (solar keratosis): sun damage, not cancer, Keratinocyte cancer (and why 'non-melanoma skin cancer' is being retired), Bowen's disease (squamous cell carcinoma in situ), Cutaneous squamous cell carcinoma.
Shares Actinic keratosis (solar keratosis): sun damage, not cancer, Keratinocyte cancer (and why 'non-melanoma skin cancer' is being retired), Bowen's disease (squamous cell carcinoma in situ), Cutaneous squamous cell carcinoma.
Shares Actinic keratosis (solar keratosis): sun damage, not cancer, Keratinocyte cancer (and why 'non-melanoma skin cancer' is being retired), Bowen's disease (squamous cell carcinoma in situ), Cutaneous squamous cell carcinoma.
Shares Rokitansky-Aschoff sinus, Papillary carcinoma of the gallbladder, Gallbladder cancer.
Shares Actinic keratosis (solar keratosis): sun damage, not cancer, Keratinocyte cancer (and why 'non-melanoma skin cancer' is being retired), Bowen's disease (squamous cell carcinoma in situ), Cutaneous squamous cell carcinoma.
Shares Papillary carcinoma of the gallbladder, Carcinoma in situ and dysplasia of the gallbladder, Gallbladder cancer.
Shares Keratinocyte cancer (and why 'non-melanoma skin cancer' is being retired), Bowen's disease (squamous cell carcinoma in situ), TNM staging, Cutaneous squamous cell carcinoma.
Shares Actinic keratosis (solar keratosis): sun damage, not cancer, Bowen's disease (squamous cell carcinoma in situ), Ductal carcinoma in situ (DCIS).