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Where the radioactive atoms for imaging and therapy actually come from: ageing reactors, new accelerators, and a scramble for actinium.
Mo-99/Tc-99m for SPECT still depends on a few research reactors (BR2, HFR Petten, OPAL, SAFARI) with accelerator alternatives from NorthStar and SHINE. Lu-177 (non-carrier-added) is supplied by ITM, SHINE, Eckert & Ziegler, Curium and NorthStar; Ac-225 supply is the binding constraint for alpha therapy, with US DOE, TerraPower Isotopes, Orano Med (Pb-212), NorthStar, Niowave, and ITM expanding. Supply agreements are now a competitive asset for radiopharma companies.
Reactor neutron capture (Lu-176→Lu-177), Th-229 decay chains and accelerator spallation (Ac-225), and electron-accelerator photonuclear routes (Mo-99) produce isotopes that are purified, calibrated, and shipped against decay.
Nothing recorded yet: a foundation, or a gap to fill.
Dependencies are what this technology cannot be delivered without: manufacturing steps, instruments, software, upstream methods. See its full chain on the map.
Query for this technology: (TITLE:"Therapeutic isotope supply chain" OR ABSTRACT:"Therapeutic isotope supply chain" OR TITLE:"Mo-99, Lu-177, Ac-225" OR ABSTRACT:"Mo-99, Lu-177, Ac-225") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225), not a curated reading list.
Shares IRE (Institut national des Radioéléments), Eckert & Ziegler, Curium, Research reactors for medical isotopes (Mo-99, Lu-177, I-131) and the tag supporting.
Shares Isotopia Molecular Imaging, Radiopharmacy and cyclotron networks, Radiopharmaceutical GMP and releasing a drug that decays and the tag supporting.
Shares Radiopharmacy and cyclotron networks, Radiopharmaceutical GMP and releasing a drug that decays and the tag supporting.
Shares Radiopharmacy and cyclotron networks, Radiopharmaceutical GMP and releasing a drug that decays and the tag supporting.
Shares Radiopharmacy and cyclotron networks, Radioligand therapy (beta emitters) and the tag supporting.
Shares Radiopharmacy and cyclotron networks and the tag supporting.
Shares Radioligand therapy (beta emitters) and the tag supporting.
Shares Radioligand therapy (beta emitters) and the tag supporting.