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A tiny, intensely radioactive source is stepped through applicators placed in or beside the tumour for a few minutes at a time, then withdrawn, so the dose is delivered from inside without leaving anything behind.
High-dose-rate brachytherapy uses a single iridium-192 (or cobalt-60) source on a cable, driven by a remote afterloader through catheters or applicators, dwelling at computed positions to sculpt the dose. It is the backbone of curative treatment for cervical cancer, where no external technique has matched it, and is used as a boost or single treatment in prostate cancer, in skin, oesophageal, bronchial and gynaecological cancers, and as the source in some breast partial-breast treatments. Sessions last minutes and are typically given in two to six fractions.
Steep dose fall-off from a source inside the target delivers very high doses to the tumour with rapid sparing of surrounding tissue; dwell times shape the distribution.
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Query for this technology: (TITLE:"High-dose-rate brachytherapy" OR ABSTRACT:"High-dose-rate brachytherapy") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about High-dose-rate brachytherapy, not a curated reading list.
Shares Brachytherapy (internal radiotherapy), Remote afterloaders for HDR brachytherapy, Brachytherapy, Prostate cancer and the tag radiation-wave1.
Shares Remote afterloaders for HDR brachytherapy and the tag radiation-wave1.
Shares Biologically effective dose (BED) and EQD2 and the tag radiation-wave1.
Shares Prostate cancer and the tag radiation-wave1.
Shares Oesophageal cancer and the tag radiation-wave1.
Shares Biologically effective dose (BED) and EQD2, Prostate cancer and the tag radiation-wave1.
Shares Prostate cancer and the tag radiation-wave1.
Shares Cervical cancer and the tag radiation-wave1.