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LMO7 (LIM domain only protein 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q8WWI1; HGNC names it "LIM domain 7".
Open Targets scores its association with cancer at 0.57 (direct and indirect evidence; datatypes literature 0.45, affected pathway 0.76, animal model 0.80, genetic association 0.48).
In plain words · LMO7 (LIM domain only protein 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
LMO7 (LIM domain only protein 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q8WWI1; HGNC names it "LIM domain 7". Locus 13q22.2 (HGNC).
No product in this corpus aims at LMO7 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1998. Earliest sequence paper UniProt cites for the protein: Nagase et al, DNA Res, 1998, "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". Source.
Sources: HGNC HGNC:6646 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q8WWI1 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000136153 (association with cancer (MONDO_0004992) 0.57; (GraphQL API, CC0))
UniProt has no function text for Q8WWI1; HGNC names it "LIM domain 7". Locus 13q22.2 (HGNC).
Query for this target: (TITLE:"LMO7" OR ABSTRACT:"LMO7" OR TITLE:"LIM domain 7" OR ABSTRACT:"LIM domain 7" OR TITLE:"LIM domain only protein 7" OR ABSTRACT:"LIM domain only protein 7" OR TITLE:"FBX20" OR ABSTRACT:"FBX20" OR TITLE:"KIAA0858" OR ABSTRACT:"KIAA0858" OR TITLE:"FBXO20" OR ABSTRACT:"FBXO20") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about LMO7, not a curated reading list.