Loading
KIAA1549 (UPF0606 protein KIAA1549) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
May play a role in photoreceptor function.
Open Targets scores its association with cancer at 0.62 (direct and indirect evidence; datatypes literature 0.25, affected pathway 0.89, genetic association 0.00, somatic mutation 0.50).
In plain words · KIAA1549 (UPF0606 protein KIAA1549) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
KIAA1549 (UPF0606 protein KIAA1549) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
May play a role in photoreceptor function. Location: Membrane; Cell projection, cilium (UniProt).
No product in this corpus aims at KIAA1549 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2000. Earliest sequence paper UniProt cites for the protein: Nagase et al, DNA Res, 2000, "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". Source.
Sources: HGNC HGNC:22219 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9HCM3 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000122778 (association with cancer (MONDO_0004992) 0.62; (GraphQL API, CC0))
May play a role in photoreceptor function. Location: Membrane; Cell projection, cilium (UniProt). Locus 7q34 (HGNC).
Query for this target: (TITLE:"KIAA1549" OR ABSTRACT:"KIAA1549" OR TITLE:"UPF0606 protein KIAA1549" OR ABSTRACT:"UPF0606 protein KIAA1549") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about KIAA1549, not a curated reading list.