Roadmaps by number of eras

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Roadmaps ordered by how many distinct eras their steps span. Top 38 of 38 roadmaps with a value; ties are broken by name. 38 of 38 roadmaps carry dated steps (100%).

#	Roadmap	Eras	Steps and status
1	Colorectal cancer roadmap: from the adenoma-carcinoma sequence and the first screening trials to total mesorectal excision, oxaliplatin, RAS testing, immunotherapy for mismatch repair-deficient disease, ctDNA-guided treatment and organ preservation	14	14 steps, 10 current or emerging
2	Triple-negative breast cancer roadmap: from a remainder defined by three negative tests to immunotherapy, antibody-drug conjugates and the residual disease problem	13	14 steps, 8 current or emerging
3	Pancreatic cancer roadmap: from Whipple's operation to gemcitabine, FOLFIRINOX, adjuvant chemotherapy, PARP inhibition, KRAS inhibition, vaccines and the surveillance question	12	12 steps, 7 current or emerging
4	Prostate cancer roadmap: from Huggins and the discovery that a cancer can depend on a hormone, through the PSA epidemic and what it cost, the androgen receptor drugs, the DNA repair subset and PSMA, to a 2032 registry watch	12	12 steps, 5 current or emerging
5	Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials	11	11 steps, 7 current or emerging
6	Lung cancer roadmap: from Doll and Hill and the naming of tobacco, through the cytotoxic plateau, computed tomography screening, EGFR and ALK, immunotherapy by PD-L1, the perioperative trials and PACIFIC, to DLL3 in small-cell disease and a 2032 registry watch	11	11 steps, 5 current or emerging
7	Lymphoma roadmap: from a jaw tumour in Uganda and the first human cancer virus to gene-expression subtypes, PET-adapted chemotherapy, CAR-T cells, bispecific antibodies and the genetics-directed trials now recruiting	11	11 steps, 8 current or emerging
8	ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment	10	10 steps, 7 current or emerging
9	Recovery and rejuvenation roadmap: cure is not enough → survivorship gets a name → the cohorts that measured the cost → exercise proven as treatment → biological ageing measured and sold → repair, if anyone funds it	10	10 steps, 5 current or emerging
10	Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment	9	9 steps, 6 current or emerging
11	AI in oncology roadmap: pattern readers → foundation models → agents in the workflow	8	8 steps, 5 current or emerging
12	Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers	8	8 steps, 5 current or emerging
13	Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants	8	8 steps, 5 current or emerging
14	Drug discovery roadmap: screening in mice → maps of dependency → designing in silico	8	9 steps, 6 current or emerging
15	Epigenetic therapy roadmap: loosening silenced genes → mutation-specific enzymes → editing the epigenome	8	8 steps, 5 current or emerging
16	Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation	8	9 steps, 6 current or emerging
17	Hormonal therapy roadmap: removing the ovaries → tamoxifen → oral degraders switched by a blood test	8	8 steps, 5 current or emerging
18	Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first	8	8 steps, 5 current or emerging
19	Radiotherapy roadmap: X-rays → shaped beams → fewer fractions, particles and FLASH	8	8 steps, 5 current or emerging
20	Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards	8	8 steps, 5 current or emerging
21	Targeted therapy roadmap: imatinib → designed for resistance → the undruggable drivers fall	8	8 steps, 5 current or emerging
22	Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on	8	8 steps, 5 current or emerging
23	ADC roadmap: from Mylotarg to bispecific and dual-payload ADCs	7	7 steps, 4 current or emerging
24	Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs	7	8 steps, 6 current or emerging
25	Diagnostics roadmap: stains → gene panels → blood tests that decide treatment	7	7 steps, 5 current or emerging
26	Paths to cures: interception, eradication, control	7	7 steps, 5 current or emerging
27	Radical oncology: what could change the war by 2035	7	7 steps, 4 current or emerging
28	Surgery roadmap: radical operations → less surgery → no surgery when a drug has done the work	7	7 steps, 5 current or emerging
29	TROP2 ADC roadmap: sacituzumab govitecan → Dato-DXd → sac-TMT → bispecifics and PET	7	7 steps, 4 current or emerging
30	Radiopharmaceutical roadmap: iodine → lutetium → actinium	6	6 steps, 3 current or emerging
31	TNBC roadmap: from 'nothing to target' to ADC + immunotherapy first line	6	6 steps, 2 current or emerging
32	Virtual cell roadmap: from bulk omics to a predictive model of a cancer cell	6	6 steps, 3 current or emerging
33	AI in the oncology clinic: from narrow cleared tools to multimodal decision support	5	5 steps, 3 current or emerging
34	Cell therapy roadmap: CD19 CAR-T → solid tumours → in vivo CAR	5	5 steps, 2 current or emerging
35	Early detection roadmap: organ screening → blood tests for many cancers	5	5 steps, 2 current or emerging
36	Immunotherapy roadmap: Coley's toxins → checkpoint inhibitors → engineered immunity	5	5 steps, 2 current or emerging
37	KRAS roadmap: undruggable → G12C → pan-RAS	5	5 steps, 2 current or emerging
38	Molecular imaging roadmap: FDG → PSMA → FAP → antigen and immune PET	5	5 steps, 2 current or emerging

How this is counted

Counts distinct values of the era field across each roadmap's steps. The context column counts the steps and how many of them are marked current or emerging.

Coverage. 38 of 38 roadmaps carry dated steps (100%). Rows with a value of zero are not listed. Nothing is weighted, imputed or averaged; the ordering is by the number shown, then by name.

Machine-readable copy: /rankings/roadmaps-by-eras/data.json. Registry: src/lib/rankings.ts.

Roadmaps by number of eras

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Roadmaps by number of eras

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