{"slug":"roadmaps-by-eras","title":"Roadmaps by number of eras","basis":"Roadmaps ordered by how many distinct eras their steps span.","metric":"Eras","context":"Steps and status","how":"Counts distinct values of the era field across each roadmap's steps. The context column counts the steps and how many of them are marked current or emerging.","coverage":{"filled":38,"of":38,"what":"roadmaps carry dated steps","share":1},"total":38,"top":38,"rows":[{"rank":1,"id":"colorectal-roadmap","name":"Colorectal cancer roadmap: from the adenoma-carcinoma sequence and the first screening trials to total mesorectal excision, oxaliplatin, RAS testing, immunotherapy for mismatch repair-deficient disease, ctDNA-guided treatment and organ preservation","kind":"roadmap","route":"/roadmaps/colorectal-roadmap/","value":14,"metric":"14","context":"14 steps, 10 current or emerging"},{"rank":2,"id":"tnbc-roadmap","name":"Triple-negative breast cancer roadmap: from a remainder defined by three negative tests to immunotherapy, antibody-drug conjugates and the residual disease problem","kind":"roadmap","route":"/roadmaps/tnbc-roadmap/","value":13,"metric":"13","context":"14 steps, 8 current or emerging"},{"rank":3,"id":"pancreatic-roadmap","name":"Pancreatic cancer roadmap: from Whipple's operation to gemcitabine, FOLFIRINOX, adjuvant chemotherapy, PARP inhibition, KRAS inhibition, vaccines and the surveillance question","kind":"roadmap","route":"/roadmaps/pancreatic-roadmap/","value":12,"metric":"12","context":"12 steps, 7 current or emerging"},{"rank":4,"id":"prostate-roadmap","name":"Prostate cancer roadmap: from Huggins and the discovery that a cancer can depend on a hormone, through the PSA epidemic and what it cost, the androgen receptor drugs, the DNA repair subset and PSMA, to a 2032 registry watch","kind":"roadmap","route":"/roadmaps/prostate-roadmap/","value":12,"metric":"12","context":"12 steps, 5 current or emerging"},{"rank":5,"id":"gallbladder-cancer-roadmap","name":"Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials","kind":"roadmap","route":"/roadmaps/gallbladder-cancer-roadmap/","value":11,"metric":"11","context":"11 steps, 7 current or emerging"},{"rank":6,"id":"lung-cancer-evidence-roadmap","name":"Lung cancer roadmap: from Doll and Hill and the naming of tobacco, through the cytotoxic plateau, computed tomography screening, EGFR and ALK, immunotherapy by PD-L1, the perioperative trials and PACIFIC, to DLL3 in small-cell disease and a 2032 registry watch","kind":"roadmap","route":"/roadmaps/lung-cancer-evidence-roadmap/","value":11,"metric":"11","context":"11 steps, 5 current or emerging"},{"rank":7,"id":"lymphoma-roadmap","name":"Lymphoma roadmap: from a jaw tumour in Uganda and the first human cancer virus to gene-expression subtypes, PET-adapted chemotherapy, CAR-T cells, bispecific antibodies and the genetics-directed trials now recruiting","kind":"roadmap","route":"/roadmaps/lymphoma-roadmap/","value":11,"metric":"11","context":"11 steps, 8 current or emerging"},{"rank":8,"id":"ctdna-tests","name":"ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment","kind":"roadmap","route":"/roadmaps/ctdna-tests/","value":10,"metric":"10","context":"10 steps, 7 current or emerging"},{"rank":9,"id":"rejuvenation-roadmap","name":"Recovery and rejuvenation roadmap: cure is not enough → survivorship gets a name → the cohorts that measured the cost → exercise proven as treatment → biological ageing measured and sold → repair, if anyone funds it","kind":"roadmap","route":"/roadmaps/rejuvenation-roadmap/","value":10,"metric":"10","context":"10 steps, 5 current or emerging"},{"rank":10,"id":"nutrition-lifestyle-roadmap","name":"Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment","kind":"roadmap","route":"/roadmaps/nutrition-lifestyle-roadmap/","value":9,"metric":"9","context":"9 steps, 6 current or emerging"},{"rank":11,"id":"ai-oncology-roadmap","name":"AI in oncology roadmap: pattern readers → foundation models → agents in the workflow","kind":"roadmap","route":"/roadmaps/ai-oncology-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":12,"id":"prevention-roadmap","name":"Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers","kind":"roadmap","route":"/roadmaps/prevention-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":13,"id":"devices-roadmap","name":"Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants","kind":"roadmap","route":"/roadmaps/devices-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":14,"id":"drug-discovery-roadmap","name":"Drug discovery roadmap: screening in mice → maps of dependency → designing in silico","kind":"roadmap","route":"/roadmaps/drug-discovery-roadmap/","value":8,"metric":"8","context":"9 steps, 6 current or emerging"},{"rank":15,"id":"epigenetics-roadmap","name":"Epigenetic therapy roadmap: loosening silenced genes → mutation-specific enzymes → editing the epigenome","kind":"roadmap","route":"/roadmaps/epigenetics-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":16,"id":"global-access-roadmap","name":"Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation","kind":"roadmap","route":"/roadmaps/global-access-roadmap/","value":8,"metric":"8","context":"9 steps, 6 current or emerging"},{"rank":17,"id":"hormonal-therapy-roadmap","name":"Hormonal therapy roadmap: removing the ovaries → tamoxifen → oral degraders switched by a blood test","kind":"roadmap","route":"/roadmaps/hormonal-therapy-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":18,"id":"paediatric-oncology-roadmap","name":"Paediatric oncology roadmap: cooperative-group cures → engineered immunity → drugs developed for children first","kind":"roadmap","route":"/roadmaps/paediatric-oncology-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":19,"id":"radiation-roadmap","name":"Radiotherapy roadmap: X-rays → shaped beams → fewer fractions, particles and FLASH","kind":"roadmap","route":"/roadmaps/radiation-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":20,"id":"survivorship-roadmap","name":"Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards","kind":"roadmap","route":"/roadmaps/survivorship-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":21,"id":"targeted-therapy-roadmap","name":"Targeted therapy roadmap: imatinib → designed for resistance → the undruggable drivers fall","kind":"roadmap","route":"/roadmaps/targeted-therapy-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":22,"id":"trial-modernisation-roadmap","name":"Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on","kind":"roadmap","route":"/roadmaps/trial-modernisation-roadmap/","value":8,"metric":"8","context":"8 steps, 5 current or emerging"},{"rank":23,"id":"adc-generations","name":"ADC roadmap: from Mylotarg to bispecific and dual-payload ADCs","kind":"roadmap","route":"/roadmaps/adc-generations/","value":7,"metric":"7","context":"7 steps, 4 current or emerging"},{"rank":24,"id":"chemotherapy-roadmap","name":"Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs","kind":"roadmap","route":"/roadmaps/chemotherapy-roadmap/","value":7,"metric":"7","context":"8 steps, 6 current or emerging"},{"rank":25,"id":"diagnostics-roadmap","name":"Diagnostics roadmap: stains → gene panels → blood tests that decide treatment","kind":"roadmap","route":"/roadmaps/diagnostics-roadmap/","value":7,"metric":"7","context":"7 steps, 5 current or emerging"},{"rank":26,"id":"cure-paths","name":"Paths to cures: interception, eradication, control","kind":"roadmap","route":"/roadmaps/cure-paths/","value":7,"metric":"7","context":"7 steps, 5 current or emerging"},{"rank":27,"id":"frontier-2035","name":"Radical oncology: what could change the war by 2035","kind":"roadmap","route":"/roadmaps/frontier-2035/","value":7,"metric":"7","context":"7 steps, 4 current or emerging"},{"rank":28,"id":"surgery-roadmap","name":"Surgery roadmap: radical operations → less surgery → no surgery when a drug has done the work","kind":"roadmap","route":"/roadmaps/surgery-roadmap/","value":7,"metric":"7","context":"7 steps, 5 current or emerging"},{"rank":29,"id":"trop2-adc-roadmap","name":"TROP2 ADC roadmap: sacituzumab govitecan → Dato-DXd → sac-TMT → bispecifics and PET","kind":"roadmap","route":"/roadmaps/trop2-adc-roadmap/","value":7,"metric":"7","context":"7 steps, 4 current or emerging"},{"rank":30,"id":"radiopharma-roadmap","name":"Radiopharmaceutical roadmap: iodine → lutetium → actinium","kind":"roadmap","route":"/roadmaps/radiopharma-roadmap/","value":6,"metric":"6","context":"6 steps, 3 current or emerging"},{"rank":31,"id":"tnbc-history","name":"TNBC roadmap: from 'nothing to target' to ADC + immunotherapy first line","kind":"roadmap","route":"/roadmaps/tnbc-history/","value":6,"metric":"6","context":"6 steps, 2 current or emerging"},{"rank":32,"id":"virtual-cell","name":"Virtual cell roadmap: from bulk omics to a predictive model of a cancer cell","kind":"roadmap","route":"/roadmaps/virtual-cell/","value":6,"metric":"6","context":"6 steps, 3 current or emerging"},{"rank":33,"id":"ai-oncology-clinic","name":"AI in the oncology clinic: from narrow cleared tools to multimodal decision support","kind":"roadmap","route":"/roadmaps/ai-oncology-clinic/","value":5,"metric":"5","context":"5 steps, 3 current or emerging"},{"rank":34,"id":"cell-therapy-roadmap","name":"Cell therapy roadmap: CD19 CAR-T → solid tumours → in vivo CAR","kind":"roadmap","route":"/roadmaps/cell-therapy-roadmap/","value":5,"metric":"5","context":"5 steps, 2 current or emerging"},{"rank":35,"id":"early-detection-roadmap","name":"Early detection roadmap: organ screening → blood tests for many cancers","kind":"roadmap","route":"/roadmaps/early-detection-roadmap/","value":5,"metric":"5","context":"5 steps, 2 current or emerging"},{"rank":36,"id":"immunotherapy-roadmap","name":"Immunotherapy roadmap: Coley's toxins → checkpoint inhibitors → engineered immunity","kind":"roadmap","route":"/roadmaps/immunotherapy-roadmap/","value":5,"metric":"5","context":"5 steps, 2 current or emerging"},{"rank":37,"id":"kras-roadmap","name":"KRAS roadmap: undruggable → G12C → pan-RAS","kind":"roadmap","route":"/roadmaps/kras-roadmap/","value":5,"metric":"5","context":"5 steps, 2 current or emerging"},{"rank":38,"id":"molecular-imaging-roadmap","name":"Molecular imaging roadmap: FDG → PSMA → FAP → antigen and immune PET","kind":"roadmap","route":"/roadmaps/molecular-imaging-roadmap/","value":5,"metric":"5","context":"5 steps, 2 current or emerging"}]}