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Applies evolutionary game theory to cancer treatment, dosing drugs to control rather than eradicate resistant clones.
Robert A. Gatenby is Chair of the Department of Radiology and Co-Director of the Center of Excellence for Evolutionary Therapy at Moffitt Cancer Center. He is a radiologist and mathematical oncologist known for applying evolutionary game theory to cancer treatment, dosing drugs to control rather than eradicate resistant clones. He founded Moffitt's Integrated Mathematical Oncology department and ran the first adaptive-therapy trial, using abiraterone in prostate cancer. His selected paper describes integrating evolutionary dynamics into the treatment of metastatic castration-resistant prostate cancer.
| Title | Journal | Year |
|---|---|---|
| Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer | Nature Communications | 2017 |
Shares Clonal evolution and the ecological view of cancer, Theories of cancer: how the ideas connect.
Shares Clonal evolution and the ecological view of cancer, Theories of cancer: how the ideas connect.
Shares Nature Communications, Clonal evolution and the ecological view of cancer, Prostate cancer.
Shares Abiraterone acetate, Prostate cancer.
Shares Moffitt Cancer Center, Drug resistance (primary and acquired), Prostate cancer.
Shares Abiraterone acetate, Prostate cancer.
Shares Abiraterone acetate, Prostate cancer.
Shares Abiraterone acetate, Prostate cancer.