The American Cancer Society's annual US report for 2023 projected about 1.96 million new cancer cases, reported a continued fall in the cancer death rate, and flagged rising prostate cancer diagnoses at advanced stage alongside a steep fall in cervical cancer among young women vaccinated against HPV.
Siegel, Miller, Wagle and Jemal projected 1,958,310 new cancer cases and 609,820 cancer deaths in the United States for 2023. The cancer death rate had fallen 33% since 1991, an estimated 3.8 million deaths averted. The report noted that prostate cancer incidence had risen by about 3% a year from 2014 to 2019 after a decade of decline, driven by advanced-stage disease, and that cervical cancer incidence in women aged 20 to 24 had fallen by 65% from 2012 to 2019, consistent with HPV vaccination.
This edition supplied two widely quoted signals: the first population-level evidence of HPV vaccination preventing cervical cancer in the United States, and the warning that reduced PSA screening was shifting prostate cancer towards later diagnosis.
Introduced the breakdown of progress by age, race and sex that exposed how unequally the decline in cancer deaths had been shared.
The clearest population-level signature of a targeted drug: the fall in chronic myeloid leukaemia deaths after imatinib.
Confirmed that the decline in incidence and deaths was reaching most population groups, while flagging the groups it was not.
Showed the fall in deaths was concentrated in a handful of common cancers where smoking decline, screening and better treatment had taken hold.
The first edition to express progress as deaths avoided, the framing every later report has kept.
One of the first editions to quantify the sustained fall in US cancer death rates that later reports tracked as deaths averted.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.
Shares Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report, Incidence versus prevalence, Mortality.