{"entity":{"id":"paper-siegel-cancer-statistics-2023-cacancer-2023","kind":"paper","name":"Siegel 2023: Cancer statistics, 2023","aka":[],"tldr":"The American Cancer Society's annual US report for 2023 projected about 1.96 million new cancer cases, reported a continued fall in the cancer death rate, and flagged rising prostate cancer diagnoses at advanced stage alongside a steep fall in cervical cancer among young women vaccinated against HPV.","summary":"Siegel, Miller, Wagle and Jemal projected 1,958,310 new cancer cases and 609,820 cancer deaths in the United States for 2023. The cancer death rate had fallen 33% since 1991, an estimated 3.8 million deaths averted. The report noted that prostate cancer incidence had risen by about 3% a year from 2014 to 2019 after a decade of decline, driven by advanced-stage disease, and that cervical cancer incidence in women aged 20 to 24 had fallen by 65% from 2012 to 2019, consistent with HPV vaccination.","asOf":"2026-09-08","links":[{"label":"Full text (DOI)","url":"https://doi.org/10.3322/caac.21763"},{"label":"ACS Cancer Facts and Figures","url":"https://www.cancer.org/research/cancer-facts-statistics.html"}],"tags":[],"related":["paper-siegel-cancer-statistics-2024-cacancer-2024"],"cancers":["prostate","cervical"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["incidence-vs-prevalence","mortality"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"journal":"CA: A Cancer Journal for Clinicians","year":2023,"doi":"10.3322/caac.21763","authors":"Siegel RL, Miller KD, Wagle NS, Jemal A.","paperType":"observational","findings":["Projected 1,958,310 new cancer cases and 609,820 cancer deaths in the United States in 2023.","Cancer death rate down 33% since 1991, about 3.8 million deaths averted.","Prostate cancer incidence rising about 3% a year from 2014 to 2019, mostly advanced-stage disease.","Cervical cancer incidence in women aged 20 to 24 down 65% from 2012 to 2019."],"whatItMeans":"This edition supplied two widely quoted signals: the first population-level evidence of HPV vaccination preventing cervical cancer in the United States, and the warning that reduced PSA screening was shifting prostate cancer towards later diagnosis.","caveats":["Projections rather than counts.","US-specific; the prostate finding relates to US screening practice."],"changedPractice":false},"route":"/key-papers/paper-siegel-cancer-statistics-2023-cacancer-2023/","neighbours":{"paper":[{"id":"paper-jemal-cancer-statistics-2007-cacancer-2007","kind":"paper","name":"Jemal 2007: Cancer statistics, 2007","route":"/key-papers/paper-jemal-cancer-statistics-2007-cacancer-2007/"},{"id":"paper-jemal-cancer-statistics-2008-cacancer-2008","kind":"paper","name":"Jemal 2008: Cancer statistics, 2008","route":"/key-papers/paper-jemal-cancer-statistics-2008-cacancer-2008/"},{"id":"paper-jemal-cancer-statistics-2009-cacancer-2009","kind":"paper","name":"Jemal 2009: Cancer statistics, 2009","route":"/key-papers/paper-jemal-cancer-statistics-2009-cacancer-2009/"},{"id":"paper-jemal-cancer-statistics-2010-cacancer-2010","kind":"paper","name":"Jemal 2010: Cancer statistics, 2010","route":"/key-papers/paper-jemal-cancer-statistics-2010-cacancer-2010/"},{"id":"paper-siegel-cancer-statistics-2013-cacancer-2013","kind":"paper","name":"Siegel 2013: Cancer statistics, 2013","route":"/key-papers/paper-siegel-cancer-statistics-2013-cacancer-2013/"},{"id":"paper-siegel-cancer-statistics-2014-cacancer-2014","kind":"paper","name":"Siegel 2014: Cancer statistics, 2014","route":"/key-papers/paper-siegel-cancer-statistics-2014-cacancer-2014/"},{"id":"paper-siegel-cancer-statistics-2024-cacancer-2024","kind":"paper","name":"Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report","route":"/key-papers/paper-siegel-cancer-statistics-2024-cacancer-2024/"}],"cancer":[{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"term":[{"id":"incidence-vs-prevalence","kind":"term","name":"Incidence versus prevalence","route":"/terms/incidence-vs-prevalence/"},{"id":"mortality","kind":"term","name":"Mortality","route":"/terms/mortality/"}]}}